L’anticorps anti-Stromal Cell Derived Factor Polyclonal Lapin est utilisé pour la détection de Stromal Cell Derived Factor dans des échantillons de Souris. Il a été validé pour IP, IHC et WB.
Aperçu rapide pour Stromal Cell Derived Factor anticorps (ABIN110540)
Antigène
Stromal Cell Derived Factor
Reactivité
Souris
Hôte
Lapin
Clonalité
Polyclonal
Application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Restrictions
For Research Use only
Format
Lyophilized
Stock
4 °C
Antigène
Stromal Cell Derived Factor
Autre désignation
SDF-1 (Stromal Cell-Derived Factor, PBSF)
Sujet
SDF-1a (stromal cell-derived factor-a)1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects ofB-cell lymphopoiesis and bone marrow myelopoiesis3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.