LARC (MIP3a, Exodus) anticorps

N° du produit ABIN110549

Détail du produit

Antigène: LARC (MIP3a, Exodus)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunoprecipitation (IP), Western Blotting (WB)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: 4 °C

Référence

Baba, Imai, Nishimura, Kakizaki, Takagi, Hieshima, Nomiyama, Yoshie: "Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC." dans: The Journal of biological chemistry, Vol. 272, Issue 23, pp. 14893-8, (1997) (PubMed).

Rossi, Vicari, Franz-Bacon, McClanahan, Zlotnik: "Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 3, pp. 1033-6, (1997) (PubMed).

Détail du antigène

Antigène: LARC (MIP3a, Exodus)

Sujet: LARC (liver and activation-regulated chemokine, MIP-3a , Exodus-1)1, 2, 3 is a 70-amino acid CC chemokine originally identified from human histiocytic lymphoma cell line U9371 and by sequence search of the EST database. This chemokine was mainly expressed in the liver and lung among various human tissues, and was also induced in several human cell lines. LARC is chemotactic for lymphocytes, weakly for neutrophils at high concentration, but not for monocytes. The LARC specific receptor has been identified as CCR64 .