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Benzo[a]pyrenediol Epoxide anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement Benzo[a]pyrenediol Epoxide dans EIA. Il présente une réactivité envers Chemical.
N° du produit ABIN1105513

Aperçu rapide pour Benzo[a]pyrenediol Epoxide anticorps (ABIN1105513)

Antigène

Benzo[a]pyrenediol Epoxide (BPDE)

Reactivité

Chemical

Hôte

Souris

Clonalité

Monoclonal

Application

Enzyme Immunoassay (EIA)

Clone

8-00E-011
  • Purification

    Protein G

    Isotype

    IgG1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Store at 2 - 8 °C.
  • Antigène

    Benzo[a]pyrenediol Epoxide (BPDE)

    Autre désignation

    Benzo(a)pyrenediol-Epoxide (BPDE)

    Classe de substances

    Chemical

    Sujet

    A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representitive PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.Synonyms: PAH, polycyclic aromatic hydrocarbon
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