CX3CL1 anticorps (Intracellular)
Aperçu rapide pour CX3CL1 anticorps (Intracellular) (ABIN110564)
Antigène
Voir toutes CX3CL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Intracellular
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Stock
- 4 °C
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- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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Autre désignation
- Fractalkine
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Sujet
- Fractalkine, also known as neurotactin, is a membrane-bound CX3C chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.
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Pathways
- Synaptic Membrane
Antigène
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