Cathepsin L anticorps

N° du produit ABIN1105700

L’anticorps Souris Monoclonal anti-Cathepsin L a été validé pour WB, IF et IHC (fro). Il convient pour détecter Cathepsin L dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cathepsin L anticorps (ABIN1105700)

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin L est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CP-L14

Détail du produit anti-Cathepsin L anticorps

Specificité: This antibody reacts to Cathepsin L1.

Purification: Affinity chromatography

Immunogène: Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS.

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cathepsin L

Antigène: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Autre désignation: Cathepsin L1

Sujet: Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins.Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

ID gène: 1514

NCBI Accession: NP_001903

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades