TYROBP anticorps

N° du produit ABIN110575

Détail du produit anti-TYROBP anticorps

Antigène: TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYROBP est non-conjugé

Application: Western Blotting (WB)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: 4 °C

Détails sur TYROBP

Antigène: TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

Autre désignation: DAP12 (TYROBP Produits)

Synonymes: anticorps TYROBP, anticorps DAP12, anticorps tyrpbp, anticorps Karap, anticorps KARAP, anticorps PLOSL, anticorps Ly83, anticorps dap12, anticorps TYRO protein tyrosine kinase binding protein, anticorps Tyro protein tyrosine kinase binding protein, anticorps TYROBP, anticorps tyrobp, anticorps Tyrobp

Sujet: : DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.