TYROBP anticorps
Aperçu rapide pour TYROBP anticorps (ABIN110575)
Antigène
Voir toutes TYROBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Stock
- 4 °C
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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Autre désignation
- DAP12
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Sujet
- : DAP12 (KARAP) is a natural killer (NK) cell-expressed cell surface receptor and belongs to the immunoglobulin and C-type lectin superfamily. Unlike other members of this family which possess immunoreceptor tyrosine-based inhibitory motifs (ITIM), DAP12 contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and is a disulfide-bonded homodimer. Crosslinking of DAP12-KIR complexes (membrane glycoproteins of the killer-cell inhibitory receptor family without an ITIM in their cytoplasmic domain) results in cellular activation.
Antigène
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