CD1a anticorps (FITC)
Aperçu rapide pour CD1a anticorps (FITC) (ABIN1106008)
Antigène
Voir toutes CD1a AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognizes the largest (49 kDa) of the three variants of the CD1 heavy chain, designated as CD1a. The 49 kDa polypeptide is associated with b2-microglobulin on human cortical thymocytes, dendritic cells and Langerhans' cells. It may also be expressed on some T cell leukemias and lymphoma. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, normal bone marrow mononuclear cells or normal tonsillar T and B lymphocytes.
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Purification
- Affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
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- CD1a
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Autre désignation
- CD1a
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Sujet
- CD1a antigen is expressed on human cortical thymocytes, dendritic cells in peripheral lymph nodes and Langerhans' cells in normal, dysplastic and neoplastic tissue. CD1 has a domain organisation similar to that of MHC Class I and its expression is inversely correlated with that of TCR and MHC Class I.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen
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ID gène
- 909
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NCBI Accession
- NP_001754
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UniProt
- P06126
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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