CD2 anticorps
Aperçu rapide pour CD2 anticorps (ABIN1106012)
Antigène
Voir toutes CD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Ion Exchange Chromatography.
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Stérilité
- 0.22 μm filtered
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Immunogène
- Human thymocytes. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS without Carrier and preservatives. This product is Sterile-filtered through 0.22 μm and treated to remove endotoxins.
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Agent conservateur
- Without preservative
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- CD2
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Autre désignation
- CD2
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Sujet
- CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
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ID gène
- 914
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NCBI Accession
- NP_001758
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UniProt
- P06729
Antigène
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