IL13RA2 anticorps

N° du produit ABIN1106072

L’anticorps anti-IL13RA2 Monoclonal Souris est utilisé pour la détection de IL13RA2 dans des échantillons de Humain. Il a été validé pour FACS, IHC (p), IHC (fro) et Func.

Aperçu rapide pour IL13RA2 anticorps (ABIN1106072)

Antigène: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL13RA2 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: B-D13

Détail du produit anti-IL13RA2 anticorps

Specificité: Recognizes the soluble antigen. Recognizes the IL-13 receptor a2 (IL-13 Ra2), a 74 kDa protein. Tested on monocyte activation (Secretion IL-6).

Purification: Ion Exchange Chromatography.

Stérilité: 0.22 μm filtered

Immunogène: IL-13Ra2 transfected CHO cell line. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline without carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove endotoxins.

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IL13RA2

Antigène: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Autre désignation: CD213a2 / IL13RA2

Sujet: IL-13 receptor alpha 2 belongs to the type I cytokine receptor family, Contains 1 fibronectin type-III domain, Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.Synonyms: IL-13R-alpha-2, IL-13RA-2, IL13 receptor alpha-2, IL13R, IL13RA2, Interleukin-13 receptor alpha-2 chain, Interleukin-13-binding protein

ID gène: 3598

NCBI Accession: NP_000631

UniProt: Q14627