CD46 anticorps

N° du produit ABIN1106417

L’anticorps Souris Monoclonal anti-CD46 a été validé pour WB, IP, Func et EIA. Il convient pour détecter CD46 dans des échantillons de Humain.

Aperçu rapide pour CD46 anticorps (ABIN1106417)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: M177

Détail du produit anti-CD46 anticorps

Specificité: The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein G

Immunogène: Purified MCP

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % bovine serum albumin

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur CD46

Antigène: CD46

Autre désignation: CD46 / MCP

Sujet: CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR).Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen

ID gène: 4179

NCBI Accession: NP_002380

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization