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CD46 anticorps

CD46 Reactivité: Humain WB, IP, Func, EIA Hôte: Souris Monoclonal M177 unconjugated
N° du produit ABIN1106417
  • Antigène Voir toutes CD46 Anticorps
    CD46
    Reactivité
    • 113
    • 39
    • 20
    • 10
    • 10
    • 1
    Humain
    Hôte
    • 84
    • 49
    • 2
    Souris
    Clonalité
    • 73
    • 62
    Monoclonal
    Conjugué
    • 50
    • 17
    • 16
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD46 est non-conjugé
    Application
    • 86
    • 78
    • 42
    • 40
    • 33
    • 14
    • 14
    • 14
    • 13
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
    Specificité
    The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP).
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Immunogène
    Purified MCP
    Clone
    M177
    Isotype
    IgG1
    Top Product
    Discover our top product CD46 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % bovine serum albumin
    Stock
    4 °C
    Stockage commentaire
    Store at 2 - 8 °C.
  • Antigène
    CD46
    Autre désignation
    CD46 / MCP (CD46 Produits)
    Synonymes
    anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
    Sujet
    CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity. It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR).Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    ID gène
    4179
    NCBI Accession
    NP_002380
    UniProt
    P15529
    Pathways
    Regulation of Actin Filament Polymerization
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