CEACAM1 anticorps (FITC)

N° du produit ABIN1106524

Détail du produit anti-CEACAM1 anticorps (FITC)

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises CD66a, a 160 kDa protein.

Purification: Ion Exchange Chromatography

Immunogène: Skin derived T cell clone

Clone: B-D60

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.09 % Sodium Azide, 5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CEACAM1

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Autre désignation: CD66a / CEACAM1 (CEACAM1 Produits)

Synonymes: anticorps BGP, anticorps BGP1, anticorps BGPI, anticorps CD66e, anticorps CEA, anticorps zeh0068, anticorps hm:zeh0068, anticorps CEACAM8, anticorps CEACAM1, anticorps MGC142545, anticorps BGPR, anticorps Bgp, anticorps CD66a, anticorps Ccam1, anticorps Bgp1, anticorps C-CAM, anticorps Cc1, anticorps Cea-1, anticorps Cea-7, anticorps Cea1, anticorps Cea7, anticorps Hv-2, anticorps Hv2, anticorps MHVR, anticorps MHVR1, anticorps Mhv-1, anticorps bb-1, anticorps mCEA1, anticorps mmCGM1, anticorps mmCGM1a, anticorps mmCGM2, anticorps carcinoembryonic antigen related cell adhesion molecule 1, anticorps carcinoembryonic antigen related cell adhesion molecule 5, anticorps carcinoembryonic antigen-related cell adhesion molecule 1, anticorps carcinoembryonic antigen-related cell adhesion molecule 6, anticorps CEACAM1, anticorps CEACAM5, anticorps ceacam1, anticorps Ceacam1, anticorps LOC101103343

Sujet: CEACAM1 (BGP/CD66a) is a transmembrane glycoprotein which belongs to the carcinoembryonic antigen (CEA) gene family. It is expressed on cells of epithelial and myeloid origin and mediates homophilic intercellular interactions that influence cellular growth, immune cell activation, and tissue morphogenesis. CEACAM1 is a putative tumour suppressor based on diminished expression in some aggressive types of cancer cells. The anti-tumour effect may be due to inhibition of tumour angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A (A1, A2) and one B domain. While the N, A1 and B domains can also be found in other CEA-family members, the A2 domain of CEACAM1 differs from those found in other CEACAM.Synonyms: BGP, BGP1, Biliary glycoprotein 1, Carcinoembryonic antigen-related cell adhesion molecule 1

ID gène: 634

NCBI Accession: NP_001020083

UniProt: P13688