CD7 anticorps (FITC)
Aperçu rapide pour CD7 anticorps (FITC) (ABIN1106542)
Antigène
Voir toutes CD7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Clone B-B7 recognizes a 40 kDa T cell and NK cell antigen.
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Purification
- Affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
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- CD7
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Autre désignation
- CD7
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Sujet
- CD7 is the earliest antigen marker expressed in the T lineage, being found on T cell precursors in fetal liver and thorax prior to thymic colonization and in thymus and bone marrow. The function of CD7 antigen is unknown and the natural ligand for CD7 has not yet been identified. CD7 monoclonal antibodies co-stimulate T cell proliferation and induce second messengers, while soluble recombinant CD7 has been reported to inhibit antigen-specific proliferation and a mixed lymphocyte reaction. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia (T-ALL). The antigen is frequently lost on large cell T cell lymphomas. The CD7 antigen may also be expressed on myeloblastic leukemias.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41
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ID gène
- 924
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NCBI Accession
- NP_006128
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UniProt
- P09564
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Pathways
- Cell-Cell Junction Organization
Antigène
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