CD8 anticorps (FITC)
Aperçu rapide pour CD8 anticorps (FITC) (ABIN1106577)
Antigène
Voir toutes CD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody detects the CD8 Molecule, expressed as a heterodimer of CD8a (32-34 kDa)and CD8b (32-34 kDa) glycoproteins. Clone MCD8 is commonly used in routine immunophenotyping, the determination of CD4/CD8 ratios in HIV/AIDS patients and aids in the identification of T cell leukemias (common T-ALL or mature T-ALL)s. MCD8 also distinguishes between chronic B and T cell lymphoid leukemias.
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Purification
- Affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
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- CD8
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Autre désignation
- CD8
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Sujet
- CD8 acts as a co-receptor with the TcR in recognizing antigens presented by MHC Class I and plays a role in the T cell-mediated immune response. The CD8 antigen is present on most tymocytes, T cytotoxic/suppressor cells and a subpopulation of NK cells.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
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ID gène
- 925
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NCBI Accession
- NP_001139345
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UniProt
- P01732
Antigène
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