Collagen Type V anticorps

N° du produit ABIN1106758

Cet anticorps Souris Monoclonal détecte spécifiquement Collagen Type V dans IHC (fro), EIA et RIA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Collagen Type V anticorps (ABIN1106758)

Antigène: Collagen Type V (COL5) (Collagen, Type V (COL5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Collagen Type V est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Clone: MC5-HA

Détail du produit anti-Collagen Type V anticorps

Specificité: The antibody reacts with native Human as well as heat denatured Human Collagen type V in RIA, ELISA and immunoblot assays. The antibody does not react with Collagen types I, II, III and IV. Human plasma proteins do not interfere with binding to collagen.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: PEG6000 precipitation + Sepharose 6B gel filtration

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 1 mL sterile water. Add preservative if preferred.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Références pour anticorps anti-Collagen Type V (ABIN1106758)

Rukosuev, Nanaev, Milovanov: "Participation of collagen types I, III, IV, V, and fibronectin in the formation of villi fibrosis in human term placenta." dans: Acta histochemica, Vol. 89, Issue 1, pp. 11-6, (1991) (PubMed).

Détails sur Collagen Type V

Antigène: Collagen Type V (COL5) (Collagen, Type V (COL5))

Autre désignation: Collagen Type V

Sujet: Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1

ID gène: 1289

NCBI Accession: NP_000084

UniProt: P20908