Collagen Type V anticorps
Aperçu rapide pour Collagen Type V anticorps (ABIN1106760)
Antigène
Voir toutes Collagen Type V (COL5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Reacts with Human pro alpha 1(V) chain.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in distilled water
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Concentration
- 1 mg/mL
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Buffer
- 0.1 M Tris, 0.1 M Glycine, 2 % Sucrose, None
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- Collagen Type V (COL5) (Collagen, Type V (COL5))
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Autre désignation
- Collagen Type V
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Sujet
- Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure.Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1
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ID gène
- 1289
Antigène
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