Cet anticorps anti-Collagen Type V Monoclonal Souris (Clone 13F6) (ABIN1106760) détecte spécifiquement Collagen Type V dans WB, IHC (fro), IP et EIA.
L’anticorps est réactif avec des échantillons de Humain.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Restore in distilled water
Concentration
1 mg/mL
Buffer
0.1 M Tris, 0.1 M Glycine, 2 % Sucrose, None
Antigène
Collagen Type V (COL5)
(Collagen, Type V (COL5))
Autre désignation
Collagen Type V
Sujet
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure.Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1