Corneodesmosin anticorps

N° du produit ABIN1106821

Cet anticorps Lapin Polyclonal détecte spécifiquement Corneodesmosin dans WB, EIA et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour Corneodesmosin anticorps (ABIN1106821)

Antigène: Corneodesmosin (CDSN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Corneodesmosin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Corneodesmosin anticorps

Specificité: This antibody reacts with Human 51 kDa CDSN protein. May cross react with proteins from other species.

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide derived from N-termiknal domain of Human CDSN.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Corneodesmosin

Antigène: Corneodesmosin (CDSN)

Autre désignation: Corneodesmosin / CDSN

Sujet: Defects in CDSN are a cause of hypotrichosis simplex of the scalp (HTSS) [MIM:146520], also known as hypotrichosis Spanish type. HTSS is an autosomal dominant form of isolated alopecia. Affected individuals have normal hair in early childhood but experience progressive loss of scalp hair beginning in the middle of the first decade and almost complete baldness by the third decade. Defects in CDSN are the cause of peeling skin syndrome type B (BPSS) [MIM:270300], also known as peeling skin syndrome or deciduous skin or keratolysis exfoliativa congenita. BPSS is a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis, associated with pruritus and atopy. It is an ichthyosiform erythroderma characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels.Synonyms: S protein

ID gène: 1041

NCBI Accession: NP_001255