CXCL10 anticorps (FITC)
Aperçu rapide pour CXCL10 anticorps (FITC) (ABIN1106856)
Antigène
Voir toutes CXCL10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein G
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Immunogène
- Recombinant human IP-10
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2 - 8 °C.
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- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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Autre désignation
- CXCL10 / IP-10
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Sujet
- IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFN gamma inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation.Synonyms: 10 kDa interferon-gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, INP10, SCYB10, Small-inducible cytokine B10
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UniProt
- P02778
Antigène
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