Cytokeratin 13 anticorps

N° du produit ABIN1106904

Cet anticorps anti-Cytokeratin 13 est un anticorps Souris Monoclonal détectant Cytokeratin 13 dans WB, IHC (p), IF, FACS et IHC (fro). Adapté pour Humain, Rat, Poisson zèbre (Danio rerio) et Cat.

Aperçu rapide pour Cytokeratin 13 anticorps (ABIN1106904)

Antigène: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivité: Humain, Rat, Poisson zèbre (Danio rerio), Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DE-K13

Détail du produit anti-Cytokeratin 13 anticorps

Specificité: DE-K13 reacts with Cytokeratin 10 and 13 in fixed cells and on frozen tissues, but exclusively with cytokeratin 13 in Formalin-Fixed, Paraffin Embedded tissues. Cytokeratin 10 is present in keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas, while Cytokeratin 13 is present in noncornified squamous epithelia, except cornea, and transitional epithelial regions, with the exception of basal cell layers of some stratified epithelia, as well as carcinomas derived from these tissues.

Réactivité croisée (Details): Species reactivity (tested):Human, Feline, Zebrafish.
Also reacts to: KRT10

Purification: Purified

Immunogène: Cytoskeletal preparation extracted from human ectocervical epithelium.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.

Détails sur Cytokeratin 13

Antigène: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Autre désignation: Cytokeratin 13

Sujet: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13

ID gène: 3860

NCBI Accession: NP_002265

UniProt: P13646