Desmoglein 2 anticorps (Extracellular Domain)

N° du produit ABIN1106982

Cet anticorps anti-Desmoglein 2 est un anticorps Souris Monoclonal détectant Desmoglein 2 dans WB, IF, FACS et IP. Adapté pour Humain.

Aperçu rapide pour Desmoglein 2 anticorps (Extracellular Domain) (ABIN1106982)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 6D8

Détail du produit anti-Desmoglein 2 anticorps

Épitope: Extracellular Domain

Specificité: The monoclonal antibody 6D8 recognizes the extracellular domain of human desmoglein-2. Does not cross react with desmoglein-1 and desmoglein-3.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein G

Immunogène: Extracellular EC4 domain

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: Desmoglein-2

Sujet: Desmogleins and desmocollins are members of the cadherin family of transmembrane proteins that together make up the core of the desmosome, a structure that provides transmembrane strength to tissues undergoing mechanical stress. The desmosomal cadherins, desmogleins and desmocollins, mediate calcium-dependent cell-cell adhesion by forming homotypic and heterotypic interactions with one another. The multiprotein desmosomal complex also includes the cytoplasmic desmosomal plaque proteins plakoglobin, phakophilins, and desmoplakin, which bind to the intracellular domain of the desmogleins and function to anchor the keratin intermediate filament network to site of cell-cell contacts.Synonyms: CDHF5, Cadherin family member 5, DSG2, HDGC

ID gène: 1829

NCBI Accession: NP_001934

UniProt: Q14126

Pathways: Cell-Cell Junction Organization