Deoxyuridine Triphosphatase (DUT) (Middle Region) anticorps

N° du produit ABIN1107021

Détail du produit

Antigène: Deoxyuridine Triphosphatase (DUT)

Épitope: Middle Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Specificité: This antibody detects DUT in the middle. No cross reactivity with other roteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence mapping at the middle region of human dUTPase .Remarks: Sequence is identical to the related rat and ouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg himerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Deoxyuridine Triphosphatase (DUT)

Autre désignation: DUT (DUT Produits)

Synonymes: anticorps BcDNA:LD08534, anticorps CG4584, anticorps Dmel\\CG4584, anticorps LD08534, anticorps UTPase, anticorps anon-SAGE:Wang-077, anticorps dUTPase, anticorps Tb07.27E10.390, anticorps dutpase, anticorps 5031412I06Rik, anticorps 5133400F09Rik, anticorps D2Bwg0749e, anticorps Dutp, anticorps PIP4, anticorps deoxyuridine triphosphatase, anticorps Deoxyuridine triphosphatase, anticorps dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50, anticorps involved in nucleotide metabolism, anticorps tegument protein, anticorps dUTPase, anticorps deoxyuridine triphosphatase L homeolog, anticorps DUT, anticorps dUTPase, anticorps P18, anticorps AlHV1gp51, anticorps UL50, anticorps HVT058, anticorps ORF9, anticorps ORF8, anticorps U45, anticorps GAMMAHV.ORF54, anticorps Tc00.1047053509151.130, anticorps Tc00.1047053508175.160, anticorps Tb927.7.5160, anticorps dut.L, anticorps Dut

Classe de substances: Viral Protein

Sujet: Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low ntracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. DUTPase ctivity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and UTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the ytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E. coli UTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial orms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the se of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this nzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.Synonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase mitochondrial, dUTP pyrophosphatase, dUTPase

ID gène: 1854

NCBI Accession: NP_001020419

UniProt: P33316