Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Deoxyuridine Triphosphatase (DUT) (C-Term) anticorps

DUT Reactivité: Humain, Rat, Souris, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN629626
  • Antigène Voir toutes Deoxyuridine Triphosphatase (DUT) Anticorps
    Deoxyuridine Triphosphatase (DUT)
    Épitope
    • 15
    • 15
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 76
    • 31
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Chien
    Hôte
    • 73
    • 2
    • 1
    Lapin
    Clonalité
    • 75
    • 1
    Polyclonal
    Conjugué
    • 27
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Inconjugué
    Application
    • 65
    • 26
    • 26
    • 25
    • 22
    • 16
    • 8
    • 6
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    DUT antibody was raised against the C terminal of DUT
    Purification
    Purified
    Immunogène
    DUT antibody was raised using the C terminal of DUT corresponding to a region with amino acids NFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN
    Top Product
    Discover our top product DUT Anticorps primaire
  • Indications d'application
    WB: 2.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    DUT Blocking Peptide, catalog no. 33R-6682, is also available for use as a blocking control in assays to test for specificity of this DUT antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DUT antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène
    Deoxyuridine Triphosphatase (DUT)
    Autre désignation
    DUT (DUT Produits)
    Synonymes
    anticorps BcDNA:LD08534, anticorps CG4584, anticorps Dmel\\CG4584, anticorps LD08534, anticorps UTPase, anticorps anon-SAGE:Wang-077, anticorps dUTPase, anticorps Tb07.27E10.390, anticorps dutpase, anticorps 5031412I06Rik, anticorps 5133400F09Rik, anticorps D2Bwg0749e, anticorps Dutp, anticorps PIP4, anticorps deoxyuridine triphosphatase, anticorps Deoxyuridine triphosphatase, anticorps dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50, anticorps involved in nucleotide metabolism, anticorps tegument protein, anticorps dUTPase, anticorps deoxyuridine triphosphatase L homeolog, anticorps DUT, anticorps dUTPase, anticorps P18, anticorps AlHV1gp51, anticorps UL50, anticorps HVT058, anticorps ORF9, anticorps ORF8, anticorps U45, anticorps GAMMAHV.ORF54, anticorps Tc00.1047053509151.130, anticorps Tc00.1047053508175.160, anticorps Tb927.7.5160, anticorps dut.L, anticorps Dut
    Classe de substances
    Viral Protein
    Sujet
    DUT is an essential enzyme of nucleotide metabolism. This protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death.
    Poids moléculaire
    19 kDa (MW of target protein)
Vous êtes ici:
Support technique