Histone H2B anticorps

N° du produit ABIN1107547

Cet anticorps Souris Monoclonal détecte spécifiquement Histone H2B dans WB, IF et IP. Il présente une réactivité envers Humain, Souris, Rat et Hamster.

Aperçu rapide pour Histone H2B anticorps (ABIN1107547)

Antigène: Histone H2B

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: C14264

Détail du produit anti-Histone H2B anticorps

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat, hamster

Purification: Protein A agarose

Immunogène: Protein fraction extracted from the mitotic chromosome

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2, without preservatives

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur Histone H2B

Antigène: Histone H2B

Sujet: The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H2B was suppressed to greater extent than that of the others, with histone H3 being relatively least affected. The analysis of acetylation status of each of the four lysine sites at the N-terminal tail of histone H2B revealed decreases consistent with those observed in the total acetylation patterns, with the K12 and K20 residues being markedly more affected than K5 and K15 residues.Synonyms: H2B Histone Family, HIST1H2B

Poids moléculaire: 14 kDa