JAM3 anticorps

N° du produit ABIN1107891

Détail du produit anti-JAM3 anticorps

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp JAM3 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Protein G

Clone: 19H36

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur JAM3

Antigène: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Autre désignation: JAM3 / JAM-C (JAM3 Produits)

Synonymes: anticorps JAM3, anticorps jam3, anticorps sr:nyz155, anticorps wu:fb30h11, anticorps wu:fc08c06, anticorps wu:fc13e04, anticorps wu:fc25g11, anticorps jamc.2, anticorps 1110002N23Rik, anticorps JAM-3, anticorps JAM-C, anticorps Jcam3, anticorps JAM-2, anticorps JAMC, anticorps junctional adhesion molecule 3, anticorps junctional adhesion molecule 3b, anticorps junctional adhesion molecule 3a, anticorps junction adhesion molecule 3, anticorps JAM3, anticorps jam3b, anticorps jam3a, anticorps Jam3

Sujet: Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: Junctional adhesion molecule 3, Junctional adhesion molecule C

ID gène: 83964

NCBI Accession: NP_075766

UniProt: Q9D8B7