Laminin gamma 1 anticorps
Aperçu rapide pour Laminin gamma 1 anticorps (ABIN1108021)
Antigène
Voir toutes Laminin gamma 1 (LAMC1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody recognizes the Mr 200,000 gamma-1-chain of Human reduced and Alkylated Laminin produced by various cultured cells, which produce Laminins complexed with it. The specificity of Mab BC17 has been confirmed by Immunoprecipitation and ELISA by using recombinant gamma-1- chain. The antibody only reacts with Human cells and tissues (further studies are going on).
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Ig Fraction
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Immunogène
- Pepsin-digested laminins from Human placenta. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide, 1.0 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
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Autre désignation
- Laminin gamma 1
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Sujet
- Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells. Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain ß1 and γ1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas.Synonyms: LAMB2, LAMC1, Laminin B2 chain, Laminin subunit gamma-1
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ID gène
- 3915
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NCBI Accession
- NP_002284
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UniProt
- P11047
Antigène
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