Lipase A anticorps
Aperçu rapide pour Lipase A anticorps (ABIN1108046)
Antigène
Voir toutes Lipase A (LIPA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to LAL.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Purified
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS, 0,03 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
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Autre désignation
- LIPA
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Sujet
- Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.Synonyms: Acid cholesteryl ester hydrolase, Cholesteryl esterase, EC=3.1.1.13, LAL, LIPA, Lipase A, Lysosomal acid lipase/cholesteryl ester hydrolase, Sterol esterase
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ID gène
- 3988
Antigène
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