MAMLD1 anticorps (N-Term)

N° du produit ABIN1108113

Cet anticorps anti-MAMLD1 est un anticorps Lapin Polyclonal détectant MAMLD1 dans WB. Adapté pour Humain, Chien, Souris et Xenopus laevis.

Aperçu rapide pour MAMLD1 anticorps (N-Term) (ABIN1108113)

Antigène: MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))

Reactivité: Humain, Chien, Souris, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAMLD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAMLD1 anticorps

Épitope: N-Term

Séquence: LEELTKIQDP SPNELDLEKI LGTKPEEPLV LDHPQATLST TPKPSVQMSH

Réactivité croisée (Details): Species reactivity (expected):Mouse, African clawed frog, DogSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogène: The immunogen for anti-CXORF6 antibody: synthetic peptide directed towards the N terminal of human CXORF6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur MAMLD1

Antigène: MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))

Autre désignation: MAMLD1

Sujet: Mastermind-like domain-containing protein 1 or CXorf6 transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. MAMLD1 is expressed in fetal brain, fetal ovary, fetal testis, adult brain, ovary, skin, testis, uterus and highly expressed in skeletal muscle. Defects in MAMLD1 are a cause of X-linked hypospadias type 2 (HYSP2). Hypospadias is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis. Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes.Mastermind-like domain-containing protein 1Synonyms: CXorf6, F18, Mastermind-like domain-containing protein 1, Protein CG1

ID gène: 10046

NCBI Accession: NP_005482