MIER1 anticorps (Middle Region)

N° du produit ABIN1108246

Cet anticorps Lapin Polyclonal détecte spécifiquement MIER1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Poulet et Xenopus laevis.

Aperçu rapide pour MIER1 anticorps (Middle Region) (ABIN1108246)

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIER1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MIER1 anticorps

Épitope: Middle Region

Séquence: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Zebrafish, African clawed frog, Chicken, Bovine, RabbitSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogène: The immunogen for anti-MIER1 antibody: synthetic peptide directed towards the middle region of human MIER1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur MIER1

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Autre désignation: MIER1

Sujet: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).Synonyms: Early response 1, Er1, KIAA1610, Mesoderm induction early response protein 1, Mi-er1, hmi-er1

ID gène: 57708

NCBI Accession: NP_065999

Pathways: Chromatin Binding