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Myeloperoxidase anticorps (C-Term)

Cet anticorps anti-Myeloperoxidase est un anticorps Lapin Polyclonal détectant Myeloperoxidase dans WB, IF et IHC (p). Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.
N° du produit ABIN1108338

Aperçu rapide pour Myeloperoxidase anticorps (C-Term) (ABIN1108338)

Antigène

Voir toutes Myeloperoxidase (MPO) Anticorps
Myeloperoxidase (MPO)

Reactivité

  • 193
  • 62
  • 54
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 150
  • 83
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 120
  • 116
Polyclonal

Conjugué

  • 102
  • 30
  • 28
  • 11
  • 9
  • 9
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Myeloperoxidase est non-conjugé

Application

  • 140
  • 87
  • 82
  • 61
  • 46
  • 43
  • 34
  • 19
  • 15
  • 14
  • 14
  • 13
  • 10
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 16
    • 12
    • 12
    • 11
    • 9
    • 8
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    This antibody detects Myeloperoxidase at C-term. No cross reactivity with other proteins.

    Réactivité croisée (Details)

    Species reactivity (tested):Human, Mouse, Rat.

    Purification

    Immunogen Affinity Chromatography

    Immunogène

    Synthetic peptide corresponding to a sequence mapping at the C-terminal of human MPO .Remarks: Sequence is identical to the related mouse and rat sequence

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Reconstitution

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Buffer

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

    Agent conservateur

    Sodium azide, Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Chang, Tseng, Lee, Hwang, Chen, Su, Chong, Lan, Wu, Chen, Lu, Liao, Hsueh, Hsieh: "β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release." dans: American journal of physiology. Lung cellular and molecular physiology, (2017) (PubMed).

  • Antigène

    Myeloperoxidase (MPO)

    Autre désignation

    Myeloperoxidase

    Sujet

    Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.Synonyms: MPO

    ID gène

    4353

    NCBI Accession

    NP_000241

    UniProt

    P05164

    Pathways

    Chromatin Binding
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