Myeloperoxidase anticorps (C-Term)

N° du produit ABIN1108338

Détail du produit anti-Myeloperoxidase anticorps

Antigène: Myeloperoxidase (MPO)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myeloperoxidase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Myeloperoxidase at C-term. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Immunogen Affinity Chromatography

Immunogène: Synthetic peptide corresponding to a sequence mapping at the C-terminal of human MPO .Remarks: Sequence is identical to the related mouse and rat sequence

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Myeloperoxidase (ABIN1108338)

Chang, Tseng, Lee, Hwang, Chen, Su, Chong, Lan, Wu, Chen, Lu, Liao, Hsueh, Hsieh: "β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release." dans: American journal of physiology. Lung cellular and molecular physiology, (2017) (PubMed).

Détails sur Myeloperoxidase

Antigène: Myeloperoxidase (MPO)

Autre désignation: Myeloperoxidase (MPO Produits)

Synonymes: anticorps mKIAA4033, anticorps MPO, anticorps LOC100335032, anticorps POX2', anticorps XPOX2', anticorps mpo, anticorps mpo-A, anticorps pmr-1, anticorps pmr1, anticorps pox2, anticorps xpox2, anticorps myeloperoxidase, anticorps myeloperoxidase L homeolog, anticorps MPO, anticorps Mpo, anticorps LOC100335032, anticorps mpo.L

Sujet: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.Synonyms: MPO

ID gène: 4353

NCBI Accession: NP_000241

UniProt: P05164

Pathways: Chromatin Binding