Myoferlin anticorps

N° du produit ABIN1108357

Cet anticorps Souris Monoclonal détecte spécifiquement Myoferlin dans WB, EIA et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Myoferlin anticorps (ABIN1108357)

Antigène: Myoferlin (MYOF)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Myoferlin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 7D2

Détail du produit anti-Myoferlin anticorps

Specificité: This antibody reacts with Human 234 kDa FER1L3 protein. Cross reacts with Mouse protein.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Détails sur Myoferlin

Antigène: Myoferlin (MYOF)

Autre désignation: Myoferlin

Sujet: Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.Synonyms: FER1L3, KIAA1207, MYOF

ID gène: 26509