PNPLA6 anticorps (C-Term)
Aperçu rapide pour PNPLA6 anticorps (C-Term) (ABIN1108496)
Antigène
Voir toutes PNPLA6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1323-1348, C-Term
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Specificité
- This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins.
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Réactivité croisée (Details)
- Species reactivity (tested):Zebrafish
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Purification
- Immunogen affinity purified
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Immunogène
- Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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Autre désignation
- NTE
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Sujet
- Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.Synonyms: Neuropathy target esterase, PNPLA6
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ID gène
- 10908
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NCBI Accession
- NP_006693
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UniProt
- Q8IY17
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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