Occludin anticorps (AA 358-504)

N° du produit ABIN1108503

Cité dans 1 publication. Cet anticorps anti-Occludin Polyclonal Cobaye (ABIN1108503) détecte spécifiquement Occludin dans WB, IF et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour Occludin anticorps (AA 358-504) (ABIN1108503)

Antigène: Occludin (OCLN)

Reactivité: Humain, Souris, Rat, Chien

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Occludin anticorps

Épitope: AA 358-504

Specificité: The polyclonal antibody reacts with Occludin.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat, Canine.

Purification: Protein A Chromatography

Immunogène: Recombinant Human Occludin (aa 358-504)

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % Sodium Azide, 0.1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8 °C.

Références pour anticorps anti-Occludin (ABIN1108503)

Liu, Gu, Zhu, Yuan, Zhu, Zhu, Yao, Hu, Zhang, Dicksved, Bao, Cai: "Epithelial Heat Shock Proteins Mediate the Protective Effects of Limosilactobacillus reuteri in Dextran Sulfate Sodium-Induced Colitis." dans: Frontiers in immunology, Vol. 13, pp. 865982, (2022) (PubMed).

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: Occludin

Sujet: Occludin is an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).Synonyms: OCLN

ID gène: 100506658

NCBI Accession: NP_001192183

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C