PAX6 anticorps (Internal Region)

N° du produit ABIN1108593

Détail du produit anti-PAX6 anticorps

Antigène: PAX6 (Paired Box 6 (PAX6))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide derived from internal part of Human PAX6 protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PAX6

Antigène: PAX6 (Paired Box 6 (PAX6))

Autre désignation: PAX6 (PAX6 Produits)

Synonymes: anticorps pax6, anticorps an2, anticorps mgda, anticorps wagr, anticorps pax-6, anticorps pax6a, anticorps xpax6, anticorps XLPAX6, anticorps MGC52531, anticorps PAX-6, anticorps AN, anticorps AN2, anticorps D11S812E, anticorps MGDA, anticorps WAGR, anticorps Pax-6, anticorps pax6b, anticorps 1500038E17Rik, anticorps AEY11, anticorps Dey, anticorps Gsfaey11, anticorps Sey, anticorps PAXZF-A, anticorps Pax6.1, anticorps cb280, anticorps fc20e07, anticorps pax-a, anticorps pax[zf-a], anticorps paxzfa, anticorps wu:fc20e07, anticorps zfpax-6a, anticorps zfpax-6b, anticorps paired box 6, anticorps paired box 6 L homeolog, anticorps paired box 6 S homeolog, anticorps paired box 6a, anticorps PAX6, anticorps pax6, anticorps Pax6, anticorps pax6.L, anticorps pax6.S, anticorps pax6a

Sujet: PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6

ID gène: 5080

NCBI Accession: NP_000271

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis