SCD anticorps

N° du produit ABIN1108939

Détail du produit anti-SCD anticorps

Antigène: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SCD est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to SCD / SCD1.

Purification: Affinity Purified

Immunogène: Full length recombinant protein

Clone: CD-E10

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS, pH 7.4 with 0.05 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SCD

Antigène: SCD (Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD))

Autre désignation: SCD / SCD1 (SCD Produits)

Synonymes: anticorps FADS5, anticorps MSTP008, anticorps SCD1, anticorps SCDOS, anticorps AA589638, anticorps AI265570, anticorps Scd, anticorps Scd-1, anticorps ab, anticorps SCD, anticorps fads5, anticorps scd1, anticorps scdos, anticorps F27J15.17, anticorps F27J15_17, anticorps STOMATAL CYTOKINESIS-DEFECTIVE 1, anticorps cds2, anticorps desaturase, anticorps stearoyl-CoA desaturase, anticorps acyl-CoA desaturase, anticorps Acyl-CoA desaturase, anticorps stearoyl-Coenzyme A desaturase 1, anticorps stearoyl-CoA desaturase (delta-9-desaturase), anticorps stearoyl-CoA desaturase (delta-9-desaturase) S homeolog, anticorps stomatal cytokinesis defective / SCD1 protein (SCD1), anticorps acyl-CoA desaturase-like, anticorps SCD, anticorps CIMG_08158, anticorps VIBHAR_RS23280, anticorps acod, anticorps Scd1, anticorps Scd, anticorps scd, anticorps LOC100346561, anticorps scd.S, anticorps SCD1, anticorps LOC100719661, anticorps LOC101835884, anticorps LOC109101093

Sujet: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa, ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders.Synonyms: Acyl-CoA desaturase, Delta(9)-desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase

ID gène: 6319

NCBI Accession: NP_005054

UniProt: O00767

Pathways: Brown Fat Cell Differentiation