SFTPB anticorps

N° du produit ABIN1108992

Cet anticorps anti-SFTPB Polyclonal Lapin (ABIN1108992) détecte spécifiquement SFTPB dans WB, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Porc, Souris et Boeuf (Vache).

Aperçu rapide pour SFTPB anticorps (ABIN1108992)

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Reactivité: Humain, Porc, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFTPB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SFTPB anticorps

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, bovine, pig

Purification: Protein A

Immunogène: Human-based 60-amino acid synthetic SP-B polypeptide

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.

Détails sur SFTPB

Antigène: SFTPB (Surfactant Protein B (SFTPB))

Autre désignation: SFTPB

Sujet: There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant. SP-B is synthesized by the alveolar type II epithelial cells as a 40-42 kD precursor that is subsequently proteolytically processed to 7.8-8 kD. SP-B enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-B is essential for air-breathing in mammals and is therefore largely conserved. SP-B can interact with both phospholipid head groups and fatty chains and is particularly active in enhancing surface active behaviour in endogenous and exogenous lung surfactants. Even low SP-B contents had measurable effects in increasing the adsorption, dynamic surface tension lowering, and/or film respreading of DPPC, mixed synthetic lipids, and column-purified lung surfactant phospholipids. Deficiency of SP-B and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).Synonyms: 18 kDa pulmonary-surfactant protein, Pulmonary surfactant-associated protein B, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTP3, SP-B, Surfactant protein B

ID gène: 9606

UniProt: P07988