SHOX2 anticorps (Middle Region)

N° du produit ABIN1109006

Détail du produit anti-SHOX2 anticorps

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHOX2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR

Réactivité croisée (Details): Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogène: The immunogen for anti-SHOX2 antibody: synthetic peptide directed towards the middle region of human SHOX2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur SHOX2

Antigène: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Autre désignation: SHOX2 / SHOT (SHOX2 Produits)

Synonymes: anticorps SHOX2, anticorps og12, anticorps shot, anticorps og12x, anticorps ogi2x, anticorps OG12, anticorps OG12X, anticorps SHOT, anticorps 6330543G17Rik, anticorps Og12x, anticorps Prx3, anticorps zgc:65884, anticorps zgc:77344, anticorps short stature homeobox 2, anticorps SHOX2, anticorps shox2, anticorps Shox2

Sujet: SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.Synonyms: Homeobox protein Og12X, OG12X, Paired-related homeobox protein SHOT, Short stature homeobox protein 2

ID gène: 6474

NCBI Accession: NP_006875

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development