TGFB2 anticorps (N-Term)

N° du produit ABIN1109226

Cet anticorps anti-TGFB2 est un anticorps Lapin Polyclonal détectant TGFB2 dans WB, IHC (fro) et EIA. Adapté pour Humain.

Aperçu rapide pour TGFB2 anticorps (N-Term) (ABIN1109226)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Détail du produit anti-TGFB2 anticorps

Épitope: N-Term

Specificité: Reacts with Human 48 kDa TGFB2 protein.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide derived from N-terminal domain of Human TGFB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in distilled water.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer

Détails sur TGFB2

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGF-beta-2 (TGFB2)

Sujet: Transforming growth factor beta's (TGF beta's) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGF beta's mediate many cell-cell interactions that occur during embryonic development. Three TGF beta's have been identified in mammals. TGFB1, TGFB2 and TGFB3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFB3 protein has approximately 80 % identity to the mature region of both TGFB1 and TGFB2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, Transforming growth factor beta-2

ID gène: 7042

NCBI Accession: NP_001129071

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus