Toxoplasma Gondii P30 anticorps

N° du produit ABIN110947

Cet anticorps Souris Monoclonal détecte spécifiquement Toxoplasma Gondii P30 dans WB, EIA et IF. Il présente une réactivité avec des échantillons de Toxoplasma gondii.

Aperçu rapide pour Toxoplasma Gondii P30 anticorps (ABIN110947)

Antigène: Toxoplasma Gondii P30

Reactivité: Toxoplasma gondii

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Clone: P30-3

Détail du produit

Purification: Affinity Chromatography on Protein G

Immunogène: Native Toxoplasma gondii p30 (purified).

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: As a guide, the end point titre in an indirect ELISA has been found to be1/2,000,000 using purified T. gondii P30 as the coating antigen. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS buffer, pH 7.2 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Toxoplasma Gondii P30

Sujet: Toxoplasma gondii p30 is the immunodominant surface antigen of Toxoplasma gondii. Toxoplasma gondii is an obligate intracellular protozoan that belongs to the class Sporozoa, and the order Eucoccidia. The parasite has an extremely wide host range and is also nonspecific with respect to the kind of cell type it can enter, making it an interesting model to study invasion. Although toxoplasmosis in healthy adults is generally asymptomatic, it produces severe disease in neonates and immunocompromised people, being the cause of death in many AIDS patients. P30 is the major surface antigen of T. gondii. It is a very abundant protein, conserved in most strains, and present both in the vesicular network of the parasitophorous vacuole and on the surface of the parasite. It is very immunogenic, eliciting high titers of antibodies in infected individuals. The gene coding for P30 has been cloned and completely sequenced: the deduced amino acid sequence shows a putative signal sequence at the N terminus, consistent with localization of P30 on the parasite's surface, as well as a short hydrophobic stretch at the C terminus.Synonyms: Major surface antigen p30

ID gène: 5811

UniProt: P13664