Vinculin anticorps

N° du produit ABIN1109492

L’anticorps anti-Vinculin Monoclonal Souris est utilisé pour la détection de Vinculin dans des échantillons de Humain. Il a été validé pour WB, IHC (fro) et EIA.

Aperçu rapide pour Vinculin anticorps (ABIN1109492)

Antigène: Vinculin (VCL)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vinculin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: FB11

Détail du produit anti-Vinculin anticorps

Specificité: The antibody reacts with the Vinculin antigen. In Immunoblotting the antibody identifies a 130 kDa polypeptide.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Purified Vinculin from Human smooth muscle. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azdie, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Vinculin

Antigène: Vinculin (VCL)

Sujet: Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and alpha actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.Synonyms: Metavinculin

ID gène: 7414

NCBI Accession: NP_003364

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2