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Vinculin anticorps
VCL
Reactivité: Humain
WB, IHC (fro), EIA
Hôte: Souris
Monoclonal
FB11
unconjugated
N° du produit ABIN1109492
Détail du produit anti-Vinculin anticorps
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Antigène
Voir toutes Vinculin (VCL) Anticorps
Vinculin (VCL)
Reactivité
Toutes les réactivités sur Vinculin Anticorps
Humain
Hôte
Toutes les hôtes sur Vinculin Anticorps
Souris
Clonalité
Toutes les clonalités sur Vinculin Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Vinculin Anticorps
Cet anticorp Vinculin est non-conjugé
Application
Tous les applications à travers Vinculin Anticorps.
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
Specificité
The antibody reacts with the Vinculin antigen. In Immunoblotting the antibody identifies a 130 kDa polypeptide.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Purified
Immunogène
Purified Vinculin from Human smooth muscle. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Clone
FB11
Isotype
IgG1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.1 mg/mL
Buffer
PBS, 0.09 % Sodium Azdie, 1 % BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Détails sur Vinculin
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Antigène
Vinculin (VCL)
Abstract
VCL Produits
Synonymes
anticorps CMD1W, anticorps CMH15, anticorps MV, anticorps MVCL, anticorps VCL, anticorps im:6902790, anticorps hm:zehn2160, anticorps DDBDRAFT_0186762, anticorps DDBDRAFT_0232320, anticorps DDB_0186762, anticorps DDB_0232320, anticorps 9430097D22, anticorps AA571387, anticorps AI462105, anticorps AW545629, anticorps CG3299, anticorps CT11081, anticorps Dmel\\CG3299, anticorps Dmvincp, anticorps EG:103B4.1, anticorps Vin, anticorps Vin2EF, anticorps vinc, anticorps LOC100228062, anticorps vcl-A, anticorps vinculin, anticorps vinculin a, anticorps vinculin A, anticorps Vinculin, anticorps vinculin S homeolog, anticorps VCL, anticorps vcla, anticorps vinA, anticorps Vcl, anticorps Vinc, anticorps CpipJ_CPIJ013873, anticorps Bm1_37935, anticorps vcl, anticorps vcl.S
Sujet
Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and alpha actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.Synonyms: Metavinculin
ID gène
7414
NCBI Accession
NP_003364
UniProt
P18206
Pathways
Cell-Cell Junction Organization , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2
Vus récemment
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