YAF2 anticorps (Middle Region)

N° du produit ABIN1109525

Détail du produit anti-YAF2 anticorps

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YAF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK

Réactivité croisée (Details): Species reactivity (expected):Dog, Rat, Mouse, Bovine, Chicken, African clawed frogSpecies reactivity (tested):Human

Purification: Purified on Protein A affinity column

Immunogène: The immunogen for anti-YAF2 antibody: synthetic peptide directed towards the middle region of human YAF2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Date de péremption: 12 months

Détails sur YAF2

Antigène: YAF2 (YY1 Associated Factor 2 (YAF2))

Autre désignation: YAF2 (YAF2 Produits)

Synonymes: anticorps MGC75686, anticorps YAF2, anticorps zgc:136577, anticorps si:ch211-155a11.5, anticorps 2810021M11Rik, anticorps YY1 associated factor 2, anticorps YY1-associated factor 2, anticorps yaf2, anticorps YAF2, anticorps LOC100221270, anticorps Yaf2

Sujet: YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.Synonyms: YY1-associated factor 2

ID gène: 10138

NCBI Accession: NP_005739