POMC anticorps (C-Term)
Aperçu rapide pour POMC anticorps (C-Term) (ABIN111034)
Antigène
Voir toutes POMC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Specificité
- Reacts with Human and Rat C-terminal ACTH. Specific for CLIP (17-39 ACTH) and does not cross-react with Synacthen (1-24 ACTH).
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Purification
- Protein A Chromatography
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Immunogène
- ACTH-BSA Conjugate Remarks:
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Isotype
- IgG1
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Indications d'application
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Reacts with solid phase ACTH either captured as part of a sandwich or adsorbed as a solidphase antigen and as such is suitable for serum assay development. Also reactive onformalin-fixed paraffin wax embedded tissue and is therefore suitable forimmunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- POMC (Proopiomelanocortin (POMC))
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Autre désignation
- POMC
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Sujet
- ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC
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ID gène
- 5443
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NCBI Accession
- NP_000930
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UniProt
- P01189
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
Antigène
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