Ferritin anticorps (Heavy & Light Chain)

N° du produit ABIN111089

L’anticorps Souris Monoclonal anti-Ferritin a été validé pour EIA et RIA. Il convient pour détecter Ferritin dans des échantillons de Humain.

Aperçu rapide pour Ferritin anticorps (Heavy & Light Chain) (ABIN111089)

Antigène: Ferritin (FE)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ferritin est non-conjugé

Application: Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Clone: 502

Détail du produit anti-Ferritin anticorps

Épitope: Heavy & Light Chain

Purification: Protein A chromatography.

Immunogène: Human Liver Ferritin

Isotype: IgG1

Information d'application

Indications d'application: Suitable for ELISA and RIA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 5.02 mg/mL (OD280 nm, E1% = 14)

Buffer: PBS, pH 7.0 with 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Ferritin

Antigène: Ferritin (FE)

Autre désignation: Ferritin

Sujet: Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis