CD9 anticorps (APC)

N° du produit ABIN1112241

Détail du produit anti-CD9 anticorps (APC)

Antigène: CD9

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD9 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Attributs du produit: Monoclonal Mouse Anti-Human CD9A is recommended for use in flow cytometry for identification of human platelets.

Purification: Affinity chromatography.

Clone: VJ1-20

Isotype: IgG2a

Information d'application

Commentaires:

Fluorescein isothiocyanate (Molecular Probes)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The conjugate is provided in liquid form in buffer containing 1% bovine serum albumin (BSA) and 0,09% Sodium azide, pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-CD9 (APC) (ABIN1112241)

Vidal-Gil, Sancho-Pelluz, Zrenner, Oltra, Sahaboglu: "Poly ADP ribosylation and extracellular vesicle activity in rod photoreceptor degeneration." dans: Scientific reports, Vol. 9, Issue 1, pp. 3758, (2019) (PubMed).

Détails sur CD9

Antigène: CD9

Autre désignation: CD9 (CD9 Produits)

Synonymes: anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Tspan29, anticorps cd9, anticorps wu:fb61g04, anticorps zgc:73383, anticorps zgc:85743, anticorps CD9 molecule, anticorps CD9 antigen, anticorps CD9 molecule a, anticorps CD9, anticorps Cd9, anticorps cd9a

Sujet: This antibody reacts with a 25 kDa molecular weight. The antigen is expressed on eosinophils, granulocytes, monocytes and numerous stromal cells. This CD9 antigen belongs to the TM4 superfamily of cell surface proteins with the N- and C-terminals cytoplasmically located. This antibody reacts immunohistochemically on frozen sections of platelets, monocytes and pre-B cells with differential staining on lymphoid and epithelial tissues. CLINICAL RELEVANCE - CD9 mAbs inhibit infection by FIV and CDV (canine distemper virus) but CD9 does not directly bind the virus, suggesting a role as a viral co-receptor, as for diphtheria toxin. - CD9 mAbs have been used for immunophenotyping leukemias and bone marrow purging in autologous bone marrow transplantation - The expression of CD9 is inversely correlated with metastasis in melanoma and breast cancer - CD9 expression is inversely correlated with actuarial survival in lung cancer Higashiyama et al. Cancer Research 55: 6040-6044 1995 - Transfection of CD9 in murine melanoma cells has been shown to reduce metastasis PRINCIPLES OF THE TEST. Immunostep CD9: APC monoclonal antibodies bind to the surface of cells that express the CD9 antigen. To identify these cells, peripheral blood leucocytes are incubated with the antibodies and red blood cells are lysed before washing to remove unbound antibodies. An appropriate fixative solution is added to lysed, washed cells before the stained and fixed cells are analysed by flow cytometry with an argon ion laser at 488nm. REAGENT COMPOSITION. Cluster Designation: CD9

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization