CD9 anticorps
Aperçu rapide pour CD9 anticorps (ABIN111240)
Antigène
Voir toutes CD9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The molecular weight of the recognized antigen is 24 kDa. This antibody recognizes 22-43 % of peripheral non-T cells (B cells) (4). Recognizes blood platelets and a few of granulous cells on normal bone marrow. Recognizes the majority of acute lymphoid leukemia, non-T, non-B, CALLA positive, some atypic or myeloid leukemias and chronic lymphoid leukemias. Recognizes the distal convoluted tubule and the distal right tubule of nephronds.
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Immunogène
- Human bone marrow malignant cells from acute non-T, non-B leukemia.
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Isotype
- IgG1
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Indications d'application
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Fluorescent Microscopy or Flow Cytometry: 2 μg/5x10e5 cells/test. Immunohistochemistry on Frozen Sections or Cell smears: 1/25-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 1m l distilled water.
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Concentration
- 0.2 mg/mL (prior lyophilization)
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Buffer
- Lyophilized from PBS containing 1 mg/mL BSA as stabilizer without preservatives.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 4 - 8 °C for one month or at -20 °C for longer.
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- CD9
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Autre désignation
- CD9
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Sujet
- CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
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ID gène
- 928
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NCBI Accession
- NP_001760
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UniProt
- P21926
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Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
Antigène
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