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CD56 anticorps (APC)

Cet anticorps anti-CD56 est un anticorps Souris Monoclonal détectant CD56 dans FACS. Adapté pour Humain et Primate.
N° du produit ABIN111261

Aperçu rapide pour CD56 anticorps (APC) (ABIN111261)

Antigène

Voir toutes CD56 (NCAM1) Anticorps
CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivité

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Humain, Primate

Hôte

  • 213
  • 111
  • 4
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Souris

Clonalité

  • 241
  • 85
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Monoclonal

Conjugué

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Cet anticorp CD56 est conjugé à/à la APC

Application

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Flow Cytometry (FACS)

Clone

MEM-188
  • Specificité

    The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

    Réactivité croisée (Details)

    Species reactivity (tested):Human, Non-Human Primates

    Purification

    Size-Exclusion Chromatography

    Immunogène

    KG-1 human acute myelogenous leukaemia cell line

    Isotype

    IgG2a
  • Indications d'application

    Flow Cytometry: Use 10 μL to label 10^6 cells or 100 μL whole blood or blood or 10^6 cells ina suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade BSA (Protease free) as a stabilizing agent, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody prior to reconstitution at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • Antigène

    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

    Autre désignation

    CD56

    Sujet

    CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1

    ID gène

    4684

    NCBI Accession

    NP_000606

    UniProt

    P13591
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