CD56 anticorps (APC)
Aperçu rapide pour CD56 anticorps (APC) (ABIN111261)
Antigène
Voir toutes CD56 (NCAM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Non-Human Primates
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Purification
- Size-Exclusion Chromatography
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Immunogène
- KG-1 human acute myelogenous leukaemia cell line
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Isotype
- IgG2a
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Indications d'application
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Flow Cytometry: Use 10 μL to label 10^6 cells or 100 μL whole blood or blood or 10^6 cells ina suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade BSA (Protease free) as a stabilizing agent, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody prior to reconstitution at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Autre désignation
- CD56
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Sujet
- CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
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ID gène
- 4684
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NCBI Accession
- NP_000606
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UniProt
- P13591
Antigène
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