CD56 anticorps

N° du produit ABIN111265

Cet anticorps Souris Monoclonal détecte spécifiquement CD56 dans FACS, WB, IP et IHC (p). Il présente une réactivité envers Humain et Primate.

Aperçu rapide pour CD56 anticorps (ABIN111265)

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD56 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-188

Détail du produit anti-CD56 anticorps

Specificité: The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with Rhesus Monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

Réactivité croisée (Details): Species reactivity (tested):Human and non-Human Primates.

Purification: Affinity Chromatography on Protein A

Immunogène: KG-1 Human acute myelogenous leukaemia cell line

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot. Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50Pretreatment: Heat retrieval (microwave oven) in citrate buffer standard ABC visualization. Positive Tissue: Positive membrane-specific reaction in adjacent peripheral nerve Stainingof paraprostatic autonomic ganglion. Staining technique: Standard ABC technique (DAB+).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD56

Antigène: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Autre désignation: CD56

Sujet: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1

ID gène: 4684

NCBI Accession: NP_000606

UniProt: P13591