TTR anticorps

N° du produit ABIN1112826

Cet anticorps anti-TTR est un anticorps Souris Monoclonal détectant TTR dans WB. Adapté pour Humain.

Aperçu rapide pour TTR anticorps (ABIN1112826)

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB)

Clone: F28

Détail du produit anti-TTR anticorps

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to the region of human PA.

Isotype: IgG2b

Information d'application

Indications d'application: WB (1:5000). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Date de péremption: 12 months

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: Prealbumin, PA

Sujet: Prealbumin (PA), as known as Transthyretin (TTR), is an evolutionarily conserved serum and cerebrospinal fluid (CSF) protein that transports holo-retinol-binding protein (RBP) and thyroxine (T4). It is a 62-kDa homotetramer with a dimer of dimers quaternary structure that is synthesized mainly in liver, choroid plexus, retinal pigment epithelium for secretion into the bloodstream, cerebrospinal fluid and the eye, respectively. It maintains normal levels of retinol, retinol-binding protein, and thyroid hormone in the circulating plasma. TTR misfolding and aggregation is known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC).

Pathways: Hormone Transport