beta Endorphin anticorps

N° du produit ABIN111317

L’anticorps anti-beta Endorphin Monoclonal Souris est utilisé pour la détection de beta Endorphin dans des échantillons de Humain. Il a été validé pour IHC (fro), IHC (p) et IF.

Aperçu rapide pour beta Endorphin anticorps (ABIN111317)

Antigène: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Endorphin est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: B31-15

Détail du produit anti-beta Endorphin anticorps

Purification: Affinity chromatography on Protein A

Immunogène: Human beta endorphin (full length native protein).

Isotype: IgG1

Information d'application

Indications d'application: Immunofluorescence. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: Microwave pretreatment is recommended. Recommended positive Control: Human pituitary gland.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur beta Endorphin

Antigène: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Autre désignation: beta Endorphin

Sujet: Beta-Endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-Endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). Beta-Endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the μ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects. Beta-Endorphin occurs in cells in the anterior pituitary. Beta-Endorphin may be detected in tumors of the pituitary, gastroinestinal and bronchial carcinoids. Absorption with 10-100 μg beta-Endorphin per ml diluted antiserum inactivates the antiserum, while Beta-lipotropin, met-enkephalin and leu-enkephalin do not.Synonyms: Endorfin-beta, Endorphin-beta

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity