beta Endorphin anticorps

N° du produit ABIN111318

Cet anticorps anti-beta Endorphin est un anticorps Souris Monoclonal détectant beta Endorphin dans IHC (fro), IHC (p) et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour beta Endorphin anticorps (ABIN111318)

Antigène: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Endorphin est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: B31-15

Détail du produit anti-beta Endorphin anticorps

Purification: Protein A affinity chromatography

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human beta-endorphin (full length native protein)

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry (paraffin sections): 10 - 20 mg/mL. Staining technique: Standard ABC technique (DAB+). Pretreatment: Heat retrieval (microwave oven). Incubation: overnight at 4 C. Positive tissue: Human pituitary gland. Immunohistochemistry (frozen sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-beta Endorphin (ABIN111318)

Millenbaugh, Baskin, DeSilva, Elliott, Glickman: "Photothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles." dans: International journal of nanomedicine, Vol. 10, pp. 1953-60, (2016) (PubMed).

Fröbel, Cadeddu, Hartwig, Bruns, Wilk, Kündgen, Fischer, Schroeder, Steidl, Germing, Lehr, Haas, Czibere: "Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1272-80, (2013) (PubMed).

Meier, Köhler, Alkhatib, Sergi, Junker, Klein, Schmidt, Fritsch: "Beta-cell development and turnover during prenatal life in humans." dans: European journal of endocrinology, Vol. 162, Issue 3, pp. 559-68, (2010) (PubMed).

Ubuka, Lai, Kitani, Suzuuchi, Pham, Cadigan, Wang, Chowdhury, Tsutsui, Bentley: "Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain." dans: The Journal of comparative neurology, Vol. 517, Issue 6, pp. 841-55, (2009) (PubMed).

Stenholm, Hakanen, Vaarno, Pihlasalo, Terho, Hänninen, Vuopio-Varkila, Huovinen, Kotilainen: "Methicillin-resistant Staphylococcus aureus screening by online immunometric monitoring of bacterial growth under selective pressure." dans: Antimicrobial agents and chemotherapy, Vol. 53, Issue 12, pp. 5088-94, (2009) (PubMed).

Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." dans: Hybridoma, Vol. 10, Issue 3, pp. 379-86, (1991) (PubMed).

Détails sur beta Endorphin

Antigène: beta Endorphin (beta-EP) (Endorphin beta (beta-EP))

Autre désignation: beta Endorphin

Sujet: Beta-Endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-Endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). Beta-Endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the μ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects. Beta-Endorphin occurs in cells in the anterior pituitary. Beta-Endorphin may be detected in tumors of the pituitary, gastroinestinal and bronchial carcinoids. Absorption with 10-100 μg beta-Endorphin per ml diluted antiserum inactivates the antiserum, while Beta-lipotropin, met-enkephalin and leu-enkephalin do not.Synonyms: Endorfin-beta, Endorphin-beta

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity